The most played game in the world is a tough one to pin down, but if I had to guess I'd say it's probably Minecraft, just because it's available on so many different platforms and has a huge following across the globe. Factors like cultural influence, accessibility, and marketing all play a role in determining which game becomes the most popular worldwide. For example, football is huge in Europe and South America, while games like League of Legends are super popular in Asia. The fact that Minecraft is relatively simple and easy to pick up has helped it become a global phenomenon, with hundreds of millions of players worldwide.